Ly Chheng's entrepreneurial spirit was evident from an early age. He started his career in the 1960s, working in various roles, including as a teacher and a government officer. However, it was not until the 1970s that he began to venture into the private sector, establishing his first business in the construction industry. This marked the beginning of his remarkable journey as an entrepreneur.

Ly Chheng is married with children, who are also involved in various business and social initiatives. His family has been a source of support throughout his career, and he credits them with instilling in him the values of hard work and social responsibility.

Ly Chheng's commitment to giving back to the community is a defining aspect of his biography. He has been actively involved in various philanthropic endeavors, focusing on education, healthcare, and social welfare. In 2000, he established the Ly Chheng Foundation, which aims to improve the lives of underprivileged Cambodians through education and skills training.

Throughout the 1980s and 1990s, Ly Chheng expanded his business interests, investing in various sectors such as real estate, agriculture, and manufacturing. His business acumen and vision for growth earned him recognition, and his companies became leading players in their respective industries. Notably, Ly Chheng's business ventures have not only generated employment opportunities but also contributed significantly to Cambodia's economic development.

Ly Chheng's contributions to Cambodian society have earned him numerous accolades. He has received awards for his entrepreneurial achievements, including the "Best Entrepreneur of the Year" award at the 2010 Cambodia Business Awards. Additionally, his philanthropic efforts have been recognized by the Cambodian government, which awarded him the "National Order of Merit" in 2015.